Many saints will apostatize when the Lawless One, the Son of Destruction, seats himself in the sanctuary of God . As the Apostle Paul explains to the Thessalonians, the “ Day of the Lord ” will not arrive until the “ Apostasy ” occurs and the “ Man of Lawlessness ” is unveiled, the one who will seat himself “ in the sanctuary of God .” Paul also labels him “ the Son of Destruction ,” but is there any additional significance to this second designation?